Biotechnology

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Early foetal sex determination using micro-volume of maternal plasma

The presence of cell-free foetal DNA (cffDNA) in maternal plasma was first discovered by Lo et al. in 1997, opening a new range of possibilities for non-invasive prenatal testing. cffDNA represents around 10% of total cell-free DNA in maternal circulation, [...]

Ultra-fast qPCR with the xxpress® qPCR Thermal Cycler

Over the last few years, qPCR has become a reference technique in the field of molecular biology due to its simplicity, sensitivity and specificity, which is reflected in the high number of publications using this method. However, qPCR is still [...]

xxpress® qPCR Thermal Cycler Comparison

Thinking of purchasing a new thermal cycler? There are lots of different factors to take into consideration; the cost involved, the compatibility of different sample formats, cycling speed and thermal uniformity are often regarded as the most important. We've already [...]

Outstanding Return on Investment with the xxpress® qPCR Thermal Cycler

There are many benefits to the xxpress® qPCR thermal cycler, one very attractive quality being the outstanding return on investment (ROI) it provides. This is an important factor for many institutions when looking to invest in a new piece of [...]

Rapid, Accurate Diagnosis of Clostridium difficile Infections

Clostridium difficile infection (CDI) is a symptomatic infectious disease caused by the anaerobic, spore-forming bacterium called Clostridium difficile. Recently CDI has become increasingly prevalent worldwide. The severity of the infection is also on the rise, meaning the requirement for a rapid and accurate method of diagnosis [...]

High-Resolution Melt with the xxpress® qPCR Thermal Cycler

A high-resolution melt (HRM) is a powerful, post-PCR analysis technique, used to identify the DNA products present. This method has a wide variety of uses from determining the specificity of a PCR reaction to detecting mutations and polymorphisms. It is [...]

It’s Biology Week!

Biology Week promotes the important and fascinating world of Bioscience, getting people of all ages and knowledge levels participating in fun and interesting life science activities. Biology week is now in its 6th year and has grown in popularity. Events [...]

2017-10-12T11:39:20+00:00 October 12th, 2017|Categories: All News, Biotechnology, Blog|Tags: , , , , |

The Future of Viral Diagnosis?

A Novel Quantitative PCR Mediated by High-Fidelity DNA Polymerase. Traditional PCR methods can be used for viral diagnosis, however they are required to be highly sensitivity, specific and reproducible for this use. These criteria are largely dependent on the complementarity [...]

Polymerase Chain Reaction: The Past, Present and Future

The polymerase chain reaction (PCR), sometimes described as ‘molecular photocopying’, is a laboratory technique that allows researchers and technicians to amplify DNA or RNA from as little as a single strand. The technology was first created in 1983 by Biochemist [...]

The Avian Influenza Virus: Distinguishing its High and Low Threat Pathotypes

Avian Influenza Virus (AIV) Pathogenicity refers to the ability of an organism to harm its host by causing disease. The avian influenza virus, subtype H7, exists as one of two pathotypes, highly pathogenic (HPAIV) and low pathogenic (LPAIV). Even LPAIV carries a [...]

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