PCR in research

Home/PCR in research

HRM for the Detection of Important Poxviruses

A high resolution melt (HRM) is a powerful, post-PCR, analysis technique used to identify the DNA products present. First of all PCR is performed with an intercalating dye present. These dyes have the unique property of only binding to double-stranded DNA. [...]

PCR a valuable tool for diagnosing HIV infections

The World Health Organisation estimates that approximately 36.7 million people are living with HIV globally. This epidemic still poses serious public health issues. Diagnosis is a key factor in helping to prevent the disease spread as well as ensuring that [...]

PCR to determine the likelihood of relapse in AML patients

Acute Myeloid Leukemia (AML) is a rare form of cancer affecting the Myeloid cells in the blood. It most commonly results from a mutation in the FMS-related Tyrosine Kinase 3 (FLT3) gene. The current treatment for AML is Allogenic Stem Cell Transplantation; [...]

A new PCR primer database for RNA virus detection

A new database has been created which outlines primers for use in the polymerase chain reaction (PCR) to detect RNA viruses. Details of this exciting new database, MRPrimerV, were published in Nucleic Acids Research.   "Abstract: Many infectious diseases are caused by viral [...]

Biomarker could predict gastric cancer survival

Chinese researchers have found an RNA biomarker that could predict survival for patients with gastric cancer, according to a paper published in the American Journal of Pathology. Gastric cancer is one of the most common cancers in developing countries. It [...]

New strategy uses PCR to improve detection of mutations in hereditary colorectal cancer

Using next generation genetic techniques and PCR could help doctors identify people with Lynch syndrome caused by a mutation in the PMS2 gene. The results are published in the Journal of Molecular Diagnostics. Lynch syndrome (also known as hereditary non-polyposis [...]

2015-08-31T17:56:09+01:00August 31st, 2015|Categories: All News, PCR in diagnosis, PCR in research, PCR news|Tags: , |

PCR helps find the genetic roots of adolescent scoliosis

A team of Japanese researchers have used PCR to help to uncover genetic clues to the cause of adolescent idiopathic scoliosis, a disease that causes curvature of the spine. The results are published in the American Journal of Human Genetics. [...]

PCR provides hints that supplements may help in Alzheimer’s

Alzheimer's disease and other forms of dementia are affecting more people worldwide every year, with a variety of factors involved, from education to genetics. Researchers have used the polymerase chain reaction (PCR) and other techniques to see if dietary supplementation [...]

2018-03-16T08:54:23+00:00July 16th, 2015|Categories: All News, PCR in research, PCR news|Tags: , , , |

Zebrafish and PCR confirm feasibility of high-throughput editing

CRISPR/Cas9 genome editing is widely used as a tool in genetic studies. Researchers looking at zebrafish have combined this technique with the polymerase chain reaction (PCR) to understand more about the functions of genes in humans. The research is published [...]

Scientists use PCR to confirm the impact of malaria in pregnancy

Low-level Plasmodium falciparum infections may not cause full-blown malaria symptoms, but they could still affect pregnant women. Researchers at the Institut de recherche pour le développement (IRD; Institute for Development Research) and the Centre d'Étude et de Recherche sur le [...]

The xxcloud is our exciting new software release, enabling users to programme and analyse results remotely, from a PC or laptop.

VISIT XXCLOUD