cancer

/Tag: cancer

RT-qPCR to Determine the Role of TEX19 in Cancers

Cancer/testis (CT) genes are one of the major groups of germline genes. They encode proteins known as cancer/testis antigens (CTAs), usually limited to the healthy adult testis. These antigens were initially identified by autologous typing, but thanks to PCR technology [...]

PCR to determine the likelihood of relapse in AML patients

Acute Myeloid Leukemia (AML) is a rare form of cancer affecting the Myeloid cells in the blood. It most commonly results from a mutation in the FMS-related Tyrosine Kinase 3 (FLT3) gene. The current treatment for AML is Allogenic Stem Cell Transplantation; [...]

PCR helps to create potential myeloma blood test

Researchers from the NIH, the National Cancer Institute (NCI), and the Dana-Farber Cancer Institute of Harvard Medical School have used the polymerase chain reaction (PCR) to help to create a potential multiple myeloma diagnostic. The results were published in the [...]

DNA alterations could be precursors of lung cancer

The polymerase chain reaction has helped a team of US researchers to see the very earliest genetic changes that could mark the onset of the most common form of lung cancer. The results are published online in Nature Communications. [...]

Biomarker could predict gastric cancer survival

Chinese researchers have found an RNA biomarker that could predict survival for patients with gastric cancer, according to a paper published in the American Journal of Pathology. Gastric cancer is one of the most common cancers in developing countries. It [...]

Leukaemia monitoring supported by PCR

The polymerase chain reaction (PCR) has a role in monitoring responses to treatment of children with acute lymphoblastic leukaemia (ALL), according to a report in the Journal of Clinical Oncology. Acute lymphoblastic leukaemia is the most common paediatric cancer. Being [...]

PCR helps find gene fusions in lung cancer

Understanding about the genetic changes behind cancer can help doctors create the best treatment patterns for patients. PCR (polymerase chain reaction) has been used to learn more about ROS1 fusion genes in lung cancer in East Asian patients, and look [...]

Using PCR to personalise lung cancer treatment

Non-small cell lung cancer (NSCLC) is the most common form of lung cancer, and the ALK inhibitors have potential in targeted treatment of the disease. However, they are only effective in patients who have rearrangements in the anaplastic lymphoma receptor [...]

Applications in PCR: PCR in IVF

PCR (polymerase chain reaction) is used in pre-implantation genetic diagnosis (PGD) in IVF (in vitro fertilisation) to screen the embryo before implantation, avoiding transfer of an embryo carrying a genetic flaw. This has a number of applications: For families at [...]

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