Groundbreaking Gene Therapy for Retinitis Pigmentosa

Retinitis Pigmentosa (RP) is an x-linked, inherited disease that causes the progressive degeneration of rod photoreceptors in the retina. This disease affects ~15,000 people in Britain and slowly leads to an irreversible form of blindness. There are several genes which [...]

PCR helps find the genetic roots of adolescent scoliosis

A team of Japanese researchers have used PCR to help to uncover genetic clues to the cause of adolescent idiopathic scoliosis, a disease that causes curvature of the spine. The results are published in the American Journal of Human Genetics. [...]

Genetic test uses qPCR to cut kidney transplant rejection

A team of researchers from the USA, Spain and Mexico have used qPCR (quantitative polymerase chain reaction) to help to develop a genetic blood test that could spot those people at risk of rejecting their transplanted kidney up to three [...]

Using PCR to personalise lung cancer treatment

Non-small cell lung cancer (NSCLC) is the most common form of lung cancer, and the ALK inhibitors have potential in targeted treatment of the disease. However, they are only effective in patients who have rearrangements in the anaplastic lymphoma receptor [...]

PCR’s role in understanding the spread of antibiotic resistance

Antibiotic resistance is a growing problem worldwide, with cases of life-threatening diseases such as tuberculosis becoming resistant to even the most powerful drugs. Polymerase chain reaction (PCR) is being used as a tool to find out more about the transmission [...]

PCR could allow sampling of embryonic DNA after IVF without biopsy

Parents who are at risk of having children with serious genetic disorders sometime choose IVF (in vitro fertilisation) followed by preimplantation genetic diagnosis (PGD) using polymerase chain reaction (PCR) to increase their chances of having a healthy baby. However, this [...]

PCR helps researchers view cellular functions

Researchers at the US Rensselaer Polytechnic Institute have created a new and very sensitive technique to detect the glycans (sugars) in living organisms. Dubbed glyco-qPCR, this uses quantitative PCR (qPCR; real-time PCR) techniques. The genome (the whole of a cell, [...]

Applications in PCR: PCR in gene expression analysis

Nearly all of the cells in an organism carry the same genetic material and so the same collection of genes, but different cells have different roles and so have different profiles of genes active at any one time. Gene expression [...]

Applications in PCR: PCR in IVF

PCR (polymerase chain reaction) is used in pre-implantation genetic diagnosis (PGD) in IVF (in vitro fertilisation) to screen the embryo before implantation, avoiding transfer of an embryo carrying a genetic flaw. This has a number of applications: For families at [...]

PCR helps uncover a blood test for an unborn baby’s sex

Wanting to know the sex of your baby can be as simple as knowing what colour to paint the nursery. However, it can also be vital to your child’s future health – there are certain disorders such as the neurological [...]

The xxcloud is our exciting new software release, enabling users to programme and analyse results remotely, from a PC or laptop.


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