genetic engineering

/Tag: genetic engineering

Design of a Synthetic Yeast Genome

A multidisciplinary team at The Department of Biomedical Engineering, Johns Hopkins University, have designed a synthetic eukaryotic genome. The project, known as Sc2.0, resulted in a highly modified Saccharomyces cerevisiae genome which was ~8% smaller, with 1.1 megabases inserted, deleted or altered. [...]

The 6-letter genetic code

A collaborative project by The Scripps Research Institute, Centre National de la Recherche Scientifique and Henan Normal University has seen a stable expansion of the genetic alphabet. Their paper has now been published in PNAS detailing the creation of a semisynthetic organism with a 6-letter [...]

PCR, from the past to the future

The polymerase chain reaction (PCR), sometimes described as 'molecular photocopying', is a laboratory technique that allows researchers and technicians to replicate and amplify DNA or RNA from small or damaged samples, even down to a single strand. The technology was [...]

Applications in PCR: PCR in genetic and genome engineering

Genetic and genome engineering is a useful tool for researchers, from producing proteins to understanding disease, and the polymerase chain reaction (PCR) has a vital role supporting this process by cloning the DNA fragments used to modify the genomes of [...]

The applications of PCR

Once an exciting new breakthrough and the subject of a Nobel Prize, PCR (polymerase chain reaction), is now used as routine technique in many laboratories. PCR, developed in 1983, amplifies DNA, allowing analysis of very small amounts of DNA, or [...]

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